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Barbara Caldwell, MS, MT(ASCP)SHCM

  • Administrative Director, Clinical Laboratory Services
  • Montgomery General Hospital
  • Olney, Maryland

There is spasms under eye 135mg colospa, however muscle relaxant whole foods order colospa 135mg, an upper limit: a point where adding more members does not increase conformity muscle relaxant pregnancy category generic colospa 135mg without prescription. At numbers beyond seven spasms gums 135 mg colospa free shipping, conformity leveled off and decreased slightly (Asch, 1955). The finding that conformity is more likely to occur when responses are public than when they are private is the reason government elections require voting in secret, so we are not coerced by others (Figure 12. The Asch effect can be easily seen in children when they have to publicly vote for something. For example, if the teacher asks whether the children would rather have extra recess, no homework, or candy, once a few children vote, the rest will comply and go with the majority. In a different classroom, the majority might vote differently, and most of the children would comply with that majority. Compliance is going along with a request or demand, even if you do not agree with the request. The correct answer to the line segment question was obvious, and it was an easy task. Researchers have categorized the motivation to conform into two types: normative social influence and informational social influence (Deutsch & Gerard, 1955). In normative social influence, people conform to the group norm to fit in, to feel good, and to be accepted by the group. However, with informational social influence, people conform because they believe the group is competent and has the correct information, particularly when the task or situation is ambiguous. Since the line judgment task was unambiguous, participants did not need to rely on the group for information. Instead, participants complied to fit in and avoid ridicule, an instance of normative social influence. An example of informational social influence may be what to do in an emergency situation. Imagine that you are in a movie theater watching a film and what seems to be smoke comes in the theater from under the emergency exit door. You are not certain that it is smoke-it might be a special effect for the movie, such as a fog machine. When you are uncertain you will tend to look at the behavior of others in the theater. However, if others seem unconcerned, you are likely to stay put and continue watching the movie (Figure 12. Many students say they would not conform, that the study is outdated, and that people nowadays are more independent. People often comply with the request because they are concerned about a consequence if they do not comply. To demonstrate this phenomenon, we review another classic social psychology experiment. Stanley Milgram was a social psychology professor at Yale who was influenced by the trial of Adolf Eichmann, a Nazi war criminal. The volunteer participants were led to believe that they were participating in a study to improve learning and memory. The participants were told that they were to teach other students (learners) correct answers to a series of test items. The participants were shown how to use a device that they were told delivered electric shocks of different intensities to the learners. The participants were told to shock the learners if they gave a wrong answer to a test item-that the shock would help them to learn. The participants gave (or believed they gave) the learners shocks, which increased in 15-volt increments, all the way up to 450 volts. The participants did not know that the learners were confederates and that the confederates did not actually receive shocks. The confederate learners cried out for help, begged the participant teachers to stop, and even complained of heart trouble. Yet, when the researcher told the participant-teachers to continue the shock, 65% of the participants continued the shock to the maximum voltage and to the point that the learner became unresponsive (Figure 12. What makes someone obey authority to the point of potentially causing serious harm to another person? Two out of three (65%) participants continued to administer shocks to an unresponsive learner. Several variations of the original Milgram experiment were conducted to test the boundaries of obedience. When certain features of the situation were changed, participants were less likely to continue to deliver shocks (Milgram, 1965). For example, when the setting of the experiment was moved to an office building, the percentage of participants who delivered the highest shock dropped to 48%. When the learner was in the same room as the teacher, the highest shock rate dropped to 40%. These variations show that when the humanity of the person being shocked was increased, obedience decreased. In a study by Martin and Bull (2008), midwives privately filled out a questionnaire regarding best practices and expectations in delivering a baby. Then, a more senior midwife and supervisor asked the junior midwives to do something they had previously stated they were opposed to . Most of the junior midwives were obedient to authority, going against their own beliefs. Whether it is due to normative or informational social influence, groups have power to influence individuals. Groupthink is the modification of the opinions of members of a group to align with what they believe is the group consensus (Janis, 1972). In group situations, the group often takes action that individuals would not perform outside the group setting because groups make more extreme decisions than individuals do. Moreover, groupthink 426 Chapter 12 Social Psychology can hinder opposing trains of thought. One example occurred when the United States led a small coalition of nations to invade Iraq in March 2003. This invasion occurred because a small group of advisors and former President George W. Bush were convinced that Iraq represented a significant terrorism threat with a large stockpile of weapons of mass destruction at its disposal. Although some of these individuals may have had some doubts about the credibility of the information available to them at the time, in the end, the group arrived at a consensus that Iraq had weapons of mass destruction and represented a significant threat to national security. It later came to light that Iraq did not have weapons of mass destruction, but not until the invasion was well underway. Here is a video of Colin Powell discussing the information he had, 10 years after his famous United Nations speech. When the group is highly cohesive, or has a strong sense of connection, maintaining group harmony may become more important to the group than making sound decisions. If the group leader is directive and makes his opinions known, this may discourage group members from disagreeing with the leader. If the group is isolated from hearing alternative or new viewpoints, groupthink may be more likely. There are several strategies that can improve group decision making including seeking outside opinions, voting in private, having the leader withhold position statements until all group members have voiced their views, conducting research on all viewpoints, weighing the costs and benefits of all options, and developing a contingency plan (Janis, 1972; Mitchell & Eckstein, 2009). Group polarization (Teger & Pruitt, 1967) is the strengthening of an original group attitude after the discussion of views within a group. That is, if a group initially favors a viewpoint, after discussion the group consensus is likely a this OpenStax book is available for free at cnx. Conversely, if the group was initially opposed to a viewpoint, group discussion would likely lead to stronger opposition. Group polarization explains many actions taken by groups that would not be undertaken by individuals. Group polarization can be observed at political conventions, when platforms of the party are supported by individuals who, when not in a group, would decline to support them. Does your opinion change if you find someone attractive, but your friends do not agree?

Better detection methods are urgently needed spasms while high generic colospa 135mg free shipping, and molecular detection methods may surpass current techniques spasms vs cramps purchase colospa 135 mg with amex. At the same time muscle relaxant hamstring discount colospa 135mg fast delivery, more effort is required to encourage adherence to the proven cancer screening modalities muscle relaxant high cheap 135 mg colospa otc. Adherence to screening is less than optimal for all the major recommended screening techniques. Not only are those who have inherited a mutation for cancer susceptibility at higher risk for developing some cancers, but often the age at onset among such individuals is younger than the age at onset in the general population. Further study is needed to establish efficacious screening protocols for those who are genetically predisposed to cancer. Finally, there are new screening modalities on the horizon, such as low-dose helical computed tomography scans for detecting early lung cancers. In screening, as in other areas of medicine and public health, the inclination to recommend screening tests on the basis of an intriguing and promising study must be balanced by a careful assessment of the evidence. Recommendations for follow-up care of individuals with an inherited predisposition to cancer. Benefits and risks of screening mammography for women in their forties: a statistical appraisal. May we agree to disagree, or how do we develop guidelines for breast cancer screening in women? The Swedish two-county trial of mammographic screening for breast cancer: recent results and calculation of benefit. Mammographic screening and mortality from breast cancer: the Malmц mammographic screening trial. Evaluation of overdiagnosis of breast cancer in screening with mammography: results of the Nijmegen programme. Mammography screening does not significantly reduce breast cancer mortality in Swedish daily practice. Effect of false-positive mammograms on interval breast cancer screening in a health maintenance organization. Relationships among objective and subjective risk for breast cancer and mammography stages of change. A randomized controlled trial of shared decision making for prostate cancer screening. Gaining informed consent for screening is difficultbut many misconceptions need to be undone. Update of the Swedish two-county program of mammographic screening for breast cancer. The Edinburgh randomised trial of breast cancer screening: results after 10 years of follow-up. Breast cancer incidence and mortality in the breast cancer detection demonstration project. Benefit of screening mammography in women aged 4049: a new meta-analysis of randomized controlled trials. Positive predictive value of screening mammography by age and family history of breast cancer. Efficacy of mammographic screening of the elderly: a case-referent study in the Nijmegen program in the Netherlands. Benefit of mammography screening in women ages 40 to 49 years: current evidence from randomized controlled trials. Trends in mortality from cervical cancer in the Nordic countries: association with organised screening programmes. Mortality from cancer of the uterus in Canada and its relationship to screening for cancer of the cervix. Working Group on Evaluation of Cervical Cancer Screening Programmes: Screening for squamous cervical cancer: duration of low risk after negative results of cervical cytology and its implications for screening policies. Use of cervical and breast cancer screening among women with and without functional limitationsUnited States, 19941995. Cytopathological findings on vaginal Papanicolaou smears after hysterectomy for benign gynecologic disease. American College of Preventive Medicine policy statement: screening for skin cancer. Changes in sun-related attitudes and behaviours, and reduced sunburn prevalence in a population at high risk of melanoma. Two decades of the public health approach to skin cancer control in Australia: why, how and where are we now? Reports by patients and dermatologists of skin cancer preventive services provided in dermatology offices. Evaluation of melanoma/skin cancer screening in Massachusetts: preliminary results. Screening for melanoma by primary health care physicians: a cost-effectiveness analysis. Spotting sinister spots: a challenge to dermatologists to examine every new patient at increased risk for signs of early melanoma. Public health perspective: the health policy implications of screening for prostate cancer. Evidence of the effects of screening in recent prostate cancer incidence, mortality, and survival rates. Cause of death misclassification and the recent rise and fall in prostate cancer mortality. Quantifying the link between population prostate-specific antigen testing and recent declines in prostate cancer mortality. Prostate-specific antigen, digital rectal examination, and transrectal ultrasonography: their roles in diagnosing early prostate cancer. Measurement of prostate-specific antigen in serum as a screening test for prostate cancer. Prostate cancer detection in a clinical urological practice by ultrasonography, digital rectal examination and prostate specific antigen. Characteristics of prostate cancer detected in the American Cancer Society National Prostate Cancer Detection Project. The relationship of prostate-specific antigen to digital rectal examination and transrectal ultrasonography. Findings of the American Cancer Society National Prostate Cancer Detection Project. Comparison of digital rectal examination and serum prostate specific antigen in the early detection of prostate cancer: results of a multicenter clinical trial of 6,630 men. An evaluation of serial digital rectal examinations in screening for prostate cancer. Annual report to the nation on the status of cancer, 19731996, with a special section on lung cancer and tobacco. Prostate cancer screening in the prostate, lung, colorectal and ovarian cancer screening trial of the National Cancer Institute. Family history of colorectal adenomatous polyps and increased risk for colorectal cancer. Case-control study of digital-rectal screening in relation to mortality from cancer of the distal rectum. Colorectal cancer mortality: effectiveness of biennial screening for fecal occult blood. Fecal occult blood screening in the Minnesota study: role of chance detection of lesions. Randomised, controlled trial of faecal occult blood screening for colorectal cancer. Randomised study of screening for colorectal cancer with faecal-occult-blood test. Screening and rescreening for colorectal cancer: a controlled trial of fecal occult blood testing in 27,700 subjects. Screening for colorectal cancer with fecal occult blood testing and sigmoidoscopy.

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Defective transport is a common mechanism of acquired methotrexate resistance in acute lymphocytic leukemia and is associated with decreased reduced folate carrier expression muscle relaxant brand names 135mg colospa. Human K562 transfectants expressing high levels of reduced folate carrier but exhibiting low transport activity spasms upper back discount colospa 135 mg. A methotrexate-resistant human breast cancer cell line with multiple defects muscle relaxant oil purchase colospa 135mg with visa, including diminished formation of methotrexate polyglutamates muscle relaxant antidote cheap colospa 135 mg. Acquisition of resistance to antifolates caused by enhanced gamma-glutamyl hydrolase activity. Methotrexate resistance in an in vivo mouse tumor due to a non-active-site dihydrofolate reductase mutation. Saturation mutagenesis at dihydrofolate reductase codons 22 and 31: a variety of amino acid substitutions conferring methotrexate resistance. Unstable amplification of an altered dihydrofolate reductase gene associated with double-minute chromosomes. Regulation of dihydrofolate reductase in human breast cancer cells and in mutant hamster cells transfected with a human dihydrofolate reductase minigene. Determinants of the sensitivity of human small-cell lung cancer cell lines to methotrexate. Differences in folylpolyglutamate synthetase and dihydrofolate reductase expression in human B-lineage versus T-lineage leukemic lymphoblasts: mechanisms for lineage differences in methotrexate polyglutamylation and cytotoxicity. Increased frequency of expression of elevated dihydrofolate reductase in T-cell versus B-precursor acute lymphoblastic leukemia in children. Methotrexate disposition in humans: case studies in ovarian cancer and following high-dose infusion. Unexpectedly high serum methotrexate levels in cystectomized bladder cancer patients with an ileal conduit treated with intermediate doses of the drug. Modulation of the antitumor effect of methotrexate by low dose leucovorin in squamous cell head and neck cancer: a randomized placebo-controlled clinical trial. Methotrexate distribution in cerebrospinal fluid after intravenous ventricular and lumbar injections. Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: evidence in terms of response rate. An alternative molecular mechanism of action of 5-fluorouracil a potent anticancer drug. Bcl-2 modulation of apoptosis induced by anticancer drugs: resistance to thymidylate stress is independent of classical resistance pathways. Quantitation of intratumoral thymidylate synthase expression predicts for response to protracted infusion of 5-fluorouracil and weekly leucovorin in disseminated colorectal cancers: preliminary report from an ongoing trial. A role for dihydropyrimidine dehydrogenase and thymidylate synthase in tumour sensitivity to fluorouracil. Decreased folylpolyglutamate synthetase expression: a novel mechanism of fluorouracil resistance. Single amino acid substitution defines a naturally occurring genetic variant of human thymidylate synthase. Thymidylate synthase gene amplification in human colon cancer cell lines resistant to 5-fluorouracil. Induction of thymidylate synthase associated with multidrug resistance in human breast and colon cancer cell lines. Regulation of thymidylate synthase in human colon cancer cells treated with 5-fluorouracil and interferon-gamma. Fluorouracil and high-dose leucovorin in previously treated patients with metastatic breast cancer. Pharmacokinetics of 5-fluorouracil assessed with a sensitive mass spectrometric method in patients on a dose escalation schedule. Severe 5-fluorouracil toxicity secondary to dihydropyrimidine dehydrogenase deficiency as a potentially more common pharmacogenetic syndrome. Dihydropyrimidine dehydrogenase pharmacogenetics in patients with colorectal cancer. A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: a Mid-Atlantic Oncology Program Study. Severe neurotoxicity following 5-fluorouracil-based chemotherapy in a patient with dihydropyrimidine dehydrogenase activity. The influence of drug interval on the effect of methotrexate and fluorouracil in the treatment of advanced colorectal cancer. Meta-analysis of randomized trials testing the biochemical modulation of fluorouracil by methotrexate in metastatic colon cancer for the Advanced Colorectal Cancer Meta-Analysis Project. Biochemical modulation of 5-fluorouracil with leucovorin or delayed uridine rescue. Interaction of interferon and 5-fluorouracil in the H630 human colon carcinoma cell line. Adjuvant 5-fluorouracil and leucovorin with or without interferon alfa-2a in colon carcinoma: National Surgical Adjuvant Breast and Bowel Project Protocol C-05. Irradiation plus 5-fluorouracil: cellular mechanisms of action and treatment schedules. Eniluracil treatment completely inactivates dihydropyrimidine dehydrogenase in colorectal tumors. Phase I clinical and pharmacology study of eniluracil plus fluorouracil in patients with advanced cancer. Es nucleoside transporter content of acute leukemia cells: role in cell sensitivity to cytarabine (araC). Intracellular pharmacodynamics of ara-C and flow cytometric analysis of cell cycle progression in leukemia chemotherapy. Determinants of sensitivity to 1-b-D-arabinofuranosylcytosine in human colon carcinoma cell lines. Structural and functional analysis of the cytidine deaminase gene in patients with acute myeloid leukemia. Substrate-specific deoxycytidine kinase deficiency in 1-b-D-arabinofuranosylcytosine-resistant leukemic cells. Effect of stem cell factor on leukemic progenitor cell growth and sensitivity to cytosine-arabinoside. Plasma and cerebrospinal fluid pharmacokinetics of 1-b-arabinofuranosylcytosine and 1-b-D-arabino-furanosyluracil following the repeated intravenous administration of high- and intermediate dose 1-b-D-arabinofuranosylcytosine. Streptococcal bacteremia in adult patients with leukemia undergoing aggressive chemotherapy: a review of 55 cases. Interferon-alpha enhances the cytotoxic and cytostatic activities of chemotherapeutic drugs in human myeloid leukemia cells. Effect of uracil arabinoside on metabolism and cytotoxicity of cytosine arabinoside in L5178Y murine leukemia. Alteration of the pharmacokinetics of high-dose ara-C by its metabolite ara-U in patients with acute leukemia. Sequence-dependent interaction of 5-fluorouracil and arabinosyl-5-azacytosine or 1-b-D-arabinofuranosylcytosine. Functional nucleoside transporters are required for gemcitabine influx and manifestation of toxicity in cancer cell lines. A review of hemolytic uremic syndrome in patients treated with gemcitabine therapy. Mechanisms of synergism between cisplatin and gemcitabine in ovarian and non-small cell lung cancer cell lines. Combination chemotherapy studies with gemcitabine and etoposide in non-small cell lung and ovarian cancer cell lines. Purine analogue 6-methylmercaptopurine riboside inhibits early and late phases of the angiogenesis process. Individualizing therapy with 6-mercaptopurine and 6-thioguanine related to the thiopurine methyltransferase genetic polymorphism. Reverse-phase high-performance liquid chromatographic assay method for quantitating 6-mercaptopurine and its methylated and non-methylated metabolites in a single sample.

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The Big Five factors are also increasingly being used in helping researchers understand the dimensions of psychological disorders muscle relaxant kidney stones colospa 135 mg on-line, such as anxiety and depression (Oldham spasms throughout body generic 135mg colospa amex, 2010; Saulsman & Page spasms kidney cheap colospa 135mg amex, 2004) spasms throat buy discount colospa 135mg line. Conscientiousness was found to be as important as intelligence in the prediction of both secondary and college academic achievement (Dumfart & Neubauer, 2016; Poropat, 2009). Individuals who are conscientious have a preference for planned rather than spontaneous behavior. Conscientiousness "I am always prepared"; "I am exacting in my work"; "I follow a schedule. Agreeableness A tendency to be compassionate and cooperative rather than suspicious and antagonistic toward others Agreeable individuals value getting along with others. They are generally considerate, friendly, generous, helpful, and willing to compromise their interests with those of others. Neuroticism "I am not usually relaxed"; "I get upset easily"; "I am easily disturbed. For example, when people enter their first serious relationship, they become more agreeable and less neurotic. Also, when we start our first job, we become more conscientious and agreeable (Vazire, 2014). Personality stability remains strong in middle adulthood (Lucas & Donnellan, 2011), however, there are slight changes in personality as one ages. According to the research, conscientiousness and agreeableness show small increases with age, while neuroticism, extraversion, and openness show slight declines with age (Lachman & Bertrand, 2001; Lucas & Donnellan, 2011; Allemand, Zimprich, & Martin, 2008). While pop psychology books with titles such as "Men are from Mars and Women are from Venus" (Gray, 1992) would suggest that men and women differ in personality, the reality is that gender differences, when present, are small, and tend to get even smaller with age. When differences are found, women tend to score slightly higher than men on conscientiousness, agreeableness, and neuroticism, and some studies show women may be slightly higher on extraversion, but only on the aspects of extraversion that involve gregariousness, warmth, and Source positive emotions, while men score higher on the assertiveness and excitement seeking aspects of extraversion (Costa, Terracciano, & McCrae, 2001; Weisberg, DeYoung, & Hirsh, 2011). The Big Five may also capture other dimensions that have been of interest to psychologists. For instance, the Big Five does not capture moral behavior (Ashton & Lee, 2008), although this variable is important in many theories of personality. There is also evidence that the Big Five factors are not the same across all cultures (Cheung & Leung, 1998). Personality will only predict behavior when the behaviors are aggregated or averaged across different situations. We might not be able to use the personality trait of friendliness to determine how friendly Malik will be on Friday night, but we can use it to predict how friendly he will be the next year in a variety of situations. When many measurements of behavior are combined, there is much clearer evidence for the stability of traits and for the effects of traits on behavior (Roberts & DelVecchio, 2000; Srivastava, John, Gosling, & Potter, 2003). Describe evidence for the effects of genetics, the environment, and interactions of the two on personality. In 2003, 35 years after she was adopted, Elyse, acting on a whim, inquired about her biological family at the adoption agency. One question that is exceedingly important for the study of personality concerns the extent to which it is the result of nature or nurture. If nature is more important, then our personalities will form early in our lives and will be difficult to change later. If nurture is more important, however, then our experiences are likely to be particularly important, and we may be able to alter our personalities over time. In this section we will see that the personality traits of humans and animals are determined in large part by their genetic makeup. Thus, it is no surprise that identical twins Paula Bernstein and Elyse Schein turned out to be very similar, even though they had been raised separately, but we will also see that genetics does not determine everything. These common genetic structures lead members of the same species to be born with a variety of behaviors that come naturally to them and that define the characteristics of the species. These abilities and characteristics are known as instincts, or complex inborn patterns of behaviors that help ensure survival and reproduction (Tinbergen, 1951). Birds naturally build nests, dogs are naturally loyal to their pack, and humans instinctively learn to walk, Source speak, and understand language. Some genes tend to increase a given characteristic and others work to decrease that same characteristic. The complex relationship among the various genes, as well as a variety of random factors, produces our personality. Furthermore, genetic factors always work with environmental factors to create personality. Having a given pattern of genes does not necessarily mean that a particular trait will develop, because some traits might occur only in some environments. For example, a person may have a genetic variant that is known to increase his or her risk for developing alcoholism, but if that person 260 never drinks because they live in a country where alcohol is not available, then the person will not become alcoholic. In addition to the effects of inheritance (nature) and environment (nurture), interactions between these two also influence personality. A high stress environment affects a genetically anxious person differently than a low stress environment. Perhaps the most direct way to study the role of genetics in personality is to selectively breed animals for the trait of interest. In this approach the scientist chooses the animals that most strongly express the personality characteristics of interest and breeds these animals with each other. If the selective breeding creates offspring with even stronger traits, then we can assume that the trait has genetic origins. In this manner, scientists have studied the role of genetics in how worms respond to stimuli, how fish develop courtship rituals, how rats differ in play, and how pigs differ in their responses to stress. Behavioral Genetics Although selective breeding studies can be informative, they are clearly not useful for studying humans. For this, psychologists rely on behavioral genetics, which is a variety of research techniques that scientists use to learn about the genetic and environmental influences on human behavior by comparing the traits of biologically and nonbiologically related family members (Baker, 2004). The presence of the trait in first-degree relatives (parents, siblings, and children) is compared to the prevalence of the trait in seconddegree relatives (aunts, uncles, grandchildren, grandparents, nephews, and nieces) and in more distant family members. A correlation coefficient is calculated that assesses the extent to which the trait for one twin is associated with the trait in the other twin. Studies on twins rely on the fact that identical (or monozygotic) twins have essentially the same set of genes, while fraternal (or dizygotic) twins have, on average, a half-identical set. In other words, if environmental factors are the same, then the only factor that can make identical twins more similar than fraternal twins is their greater genetic similarity. Monozygotic or identical twins occur when a fertilized egg splits apart in the first two weeks of development. Sometimes, however, two eggs or ova are released and fertilized by two separate sperm. These two individuals share the same amount of genetic material as would any two children from the same mother and father. Older mothers are more likely to have dizygotic twins than are younger mothers, and couples who use fertility drugs are also more likely to give birth to dizygotic twins. Consequently, there has been an increase in the number of fraternal twins recently (Bortolus et al. Source: Monozygotic Twins Source Dizygotic Twins An adoption study compares biologically related people, including twins, who have been reared either separately or apart. Evidence for genetic influence on a trait is found when children who have been adopted show traits that are more similar to those of their biological parents than to those of their adoptive parents. Although twin and adoption studies differ in their methodologies, both studies conclude that genetics is important in determining personality, as well as other cognitive (intelligence levels) and behavioral (psychopathologies) characterisitcs (Kim & Kim, 2011; Plominm, Defries, Knopik, & Neiderhiser, 2013). Results indicate that identical twins are much more similar than fraternal twins, and therefore these results strongly suggest genetic influences. Similarly, adoption studies demonstrate stronger family resemblances, even when family members are separated due to adoption. However, adoption studies do not demonstrate the level of heritability that the twin studies do (Kim & Kim, 2011). Molecular genetics is the study of which genes are associated with which personality traits (Goldsmith et al. Molecular genetics researchers have also developed new techniques that allow them to find the locations of genes within chromosomes and to identify the effects those genes have when activated or deactivated. In this approach the researchers use specialized techniques to remove or modify the influence of a gene in a line of mice (Crusio, Goldowitz, Holmes, & Wolfer, 2009). When these animals are born, they are studied to see whether their behavior differs from a control © that removing or group of normal animals. Research has foundThinkstock changing genes in mice can affect their anxiety, aggression, © Thinkstock learning, and socialization patterns.

References

  • Bernabeu-Wittel M, Canas Garcia-Otero E, et al. Infectious complications of heart transplantation. A prospective study for the first 6 years of a transplantation program. Rev Clin Esp. 1999;199(8):489-495.
  • Lee DW, Kochenderfer JN, Stetler-Stevenson M, et al. T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial. Lancet. 2015;385(9967):517-528.
  • Steiner, H., Zangerl, F., Stohr, B. et al. Results of bilateral nerve sparing laparoscopic retroperitoneal lymph node dissection for testicular cancer. J Urol 2008;180: 1348-1353.
  • Keller MA, Sellers BB Jr, Melish ME, et al: Systemic candidiasis in infants: a case presentation and literature review, Am J Dis Child 131(11):1260-1263, 1977.
  • Key TJ, Thorogood M, Appleby PN, Burr ML: Dietary habits and mortality in 11,000 vegetarians and health conscious people: Results of a 17-year follow-up. BMJ 1996;313:775-779.
  • Sand M, Gelos M, Bechara FG, et al. Epiploic appendagitisoclinical characteristics of an uncommon surgical diagnosis. BMC Surg. 2007;7:11.
  • Jolly SS, Amlani S, Hamon M, et al: Radial versus femoral access for coronary angiography or intervention and the impact on major bleeding and ischemic events: a systematic review and meta-analysis of randomized trials, Am Heart J 157(1):132-140, 2009.
  • Mochida K, Shinomiya K, Andou M: Urodynamics and electrophysiologic study of the urinary disturbances caused by cervical myelopathy, J Spinal Disord 2:141n145, 1996.
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