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Scott M. Goldman MD, FACS

  • Clinical Professor of Surgery, Jefferson Medical College, Philadelphia,
  • Pennsylvania
  • Chief of Surgery, Main Line Health System, Wynnewood,
  • Pennsylvania

Regular exercise has favorable effects on the immune system as well symptoms upper respiratory infection trusted rivastigimine 4.5mg, which may promote health symptoms hepatitis c order rivastigimine 3 mg visa, especially if you are stressed and/or depressed medications ranitidine generic rivastigimine 6mg with mastercard. Exercise is far less expensive 7 medications that cause incontinence cheap 4.5mg rivastigimine otc, and more easily accessible, than medication and psychotherapy. Plus, it has none of the side effects, such as sexual dysfunction, as seen with some antidepressants. Healthy Eating Healthy eating is another crucial part of your better lifestyles program. We think you should cook your own food, because that is the best way to have fresh and healthy ingredients and avoid preservatives. Making your own meals is also essential to making sure that you eat a lot of fruits and vegetables, which are key to good health. People who are depressed and/or have a history of childhood psychological trauma have an increase in risk for obesity as adults. Eating diets high in fat can interfere with the formation of serotonin, a neurotransmitter implicated in depression, which might affect your mood. Studies have also shown that ingestion of fat results in a temporary drop in mood. It is important to teach yourself to cook, so that you can stay away from fast food restaurants, where you are almost sure to get too much fat and too many calories, and not enough of the things you need like fresh fruits and vegetables. Relying on fast food restaurants and eating a poor diet will increase your weight and have a negative effect on your mood. That in turn will be a barrier in your pathway toward recovery from psychological trauma. A long time ago people noticed that people from Italy live longer and seemed to get less disease than people in the U. This led to the idea that maybe something about differences in diet, which came to be known as the Mediterranean Diet, could account for this. The Mediterranean Diet: reduces heart disease, stroke, diabetes, and cancer risk, prolongs life (following the Mediterranean Diet is associated with a reduction in mortality by one half over a four-year time period in some populations), cuts the number of heart attacks in half in patients with heart disease, an effect that in one study was twice as good as medication treatment. Overall, the effects of these diets were superior to medications for weight loss and the prevention of heart disease and diabetes, with fewer side effects and more positive effects on well-being. See the figure below, provided courtesy of Oldways Preservation and Exchange Trust, a nonprofit foundation dedicated to promotion of the Mediterranean Diet and other healthy behaviors. Adding folate to the diet (associated with a reduction in homocysteine in the blood) helps with symptoms of depression, and at least one study showed that taking omega-3 fatty acid supplements helped symptoms of bipolar disorder. Alcohol dependence is defined as the situation where you have to drink more to get the same effect. If you are trying to cut back without success, that may be a clue that consumption of alcohol is getting out of control. Getting into an accident, being late for work, missing work, or getting into trouble at work because of drinking or using drugs are also indicators of a problem. Being often told by friends and family that your drinking or substance use is a problem should be taken as a warning sign. Big offenders are the pain medication oxycodone, and benzodiazepines like Valium (Diazepam) and Xanax (Alprazolam). More than half of all Americans are now on at least one prescription drug, and 81% take some kind of pill. We spend twice as much money on drugs, and take twice as many drugs as other countries, but still our healthcare outcomes are second to last amongst industrialized countries. Even England is better, even though the English have a worse diet, and smoke and drink more than Americans. The Bottom Line on Better Lifestyles We recommend that you cook most of your own meals, eat fish twice a week, drink water instead of soda, use a lot of olive oil, eat a lot of fresh fruit and vegetables, add nuts to your dishes, and exercise three times a week, even if it is just taking long walks. This chapter is about being in an intimate relationship with someone with a history of psychological trauma, and is written for both the trauma survivors and their partners. Strengthening the partner bond is a key aspect of recovery from psychological trauma, because trauma victims need that intimate connection to begin to heal. This chapter is about working together to achieve your shared goals of recovering from trauma, strengthening your relationship, and achieving greater intimacy. Effects of Psychological Trauma on Relationships Traumatic stress can take a big hit on relationships. Avoidance, retreat from other people, emotional numbing, and irritability can introduce problems into any relationship, and these are all behaviors that are closely linked to psychological trauma. This is unfortunate, since the most important thing in recovery from psychological trauma is to have the love and support of our partner. You can learn how to have great relationships, just like you can learn to play the piano or drive a car. We think that everybody should take a class on relationships at some point, preferably before you get married. The most important things are honesty, trust, equality, respect, mutual support, shared goals, flexibility, and friendship. While these things are important for everyone, they are especially important for psychological trauma survivors. The more you can share about your thoughts and feelings with your partner, the greater intimacy you will have in your relationship. It also helps to counter-act the tendency that traumatized people have to feel like they are aliens, are different from other people, or that no one can understand or what they feel and have been through. Building Trust the foundation of every relationship is trust, and for psychological trauma survivors, in whom the ability to trust is wounded, this is even more important. People would rather hear what is going on with you, even if sounds negative, because being honest with your partner deepens the intimacy, and we all crave greater intimacy with others. When things go wrong and you cheat on your partner with someone else, that has a serious effect on trust. Sharing Equal Roles in a Relationship It is critical that the two persons in a partnership have equal roles. One person may bring home the big paycheck, and the other one is a stay-at-home mom without an income, but the different roles should be seen as equal. You need to make all decisions together and have equal input, whether it is about money, children, or other issues. The Importance of Shared Goals Related to having shared dreams is having shared goals. It is important for couples to explicitly outline their goals and come to an agreement about them. Make a list of what you would like to accomplish together: Where do you want to live? To do that, you will need to have frank and open discussions with your partner on a regular basis. Having shared experiences with your partner will build up trust and make your bond stronger. Find time away from work, kids, other family to sit down and have an open and honest conversation. Flexibility in the Marriage To make a marriage work, it is important to be flexible. What makes a marriage successful is the willingness of both partners to work together to overcome the problems that will inevitably arise. Having a Family Psychological trauma can have an impact on the family you create with your partner. Having a child can be a truly enriching and rewarding experience for survivors of psychological trauma. In our experience people with a history of psychological trauma who are actively trying to understand the impact of that trauma on themselves and others and who are doing the kinds of things we advocate in this book can make great parents. They often have a sort of a-ha moment where they realize that raising kids is not a pain in the ass, as they may have been led to believe in their family of origin, but is instead a rich source of meaning, love, and connection. Also, your recovery from your trauma history will give you insights and experience that you can teach to your children. In summary, we encourage you to strongly consider having a family, if there is a part of you who wants children. You do need to be mindful about how your trauma impacts your ability to work together with your partner as co-parents so that you can head off any problems.

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In 2015­17 medications on backorder discount rivastigimine 4.5mg otc, it produced dozens of original series and licensed high-quality foreign shows and movies symptoms type 1 diabetes order rivastigimine 6mg amex, including content from Netflix medications while pregnant purchase 4.5mg rivastigimine with visa. In 2018 treatment xeroderma pigmentosum discount 4.5mg rivastigimine with visa, iQiyi launched an initial public offering as it pursued an ambitious expansion of its entertainment offerings. As its membership base grew, the share of revenue from subscriptions increased from 38 percent in 2017 to 42 percent in 2018. However, even as it seeks to become a one-stop shop that can keep entertainment-hungry consumers on its platform, iQiyi is losing money. The free apps also allow consumers to "stack" services, watching what they like from each of the "big three," without spending anything more than time and attention. For those who want access to sports and exclusive content, subscription options are available. Although their ambitions to create a "one-stop shop" for entertainment and to grow their subscriber bases are delaying their arrival "in the black," Chinese video services would be in far worse financial shape without ad revenue. Indian consumers are cost-conscious, and many are willing to watch ads to access free or lower-cost video content. Affordability has put smartphones within reach of more consumers, and 400 million Indians- 38 percent of the population-now own one. The entry of new telecom providers into the Indian market in 2016 reduced the price of data plans and made streaming affordable. In 2019, there are more than 35, with offerings from broadcasters, telcos, international and regional players, as well as independent content companies. Advertisers can target their chosen demographic as part of the game using tools such as banner ads and video. Users can watch video content-including live news, original shows, and music-in 10 languages. Meanwhile, telcos such as Airtel and Vodafone are aggregating content from multiple platforms and providing a payment interface. Over 200 million Indian consumers stream video from telcos, which could grow to 375 million by 2021. The two leaders, Netflix and Amazon Prime Video, are subscription-based, with the latter included in Prime membership. Both Disney and Apple have launched subscription-only streaming services, albeit with low monthly fees intended to make the services "no-brainers" for customers. Certainly, consumers love having a choice of services, and avoiding ads is a top reason that consumers sign up for streaming video. Some viewers are especially ad-resistant, while others care less about avoiding ads than about maximizing their viewing options. That makes ad-supported services, with or without a subscription tier, an enticing option. This is especially true for media companies that cannot fund premium content without another source of revenue. Consumers consider an average of eight minutes of advertising "fair," while 16 minutes of commercials per hour is "too many" for them to watch any further. Interestingly, younger consumers (Generation Z, millennials, and Generation X) have a higher tolerance for ads than baby boomers and matures (consumers who are 72 and older). These factors make streaming services seem progressively less valuable to consumers: For the same (or a higher) price, they get less of what they want. The problem will get worse as media companies withdraw rights from competitors and launch their own streaming services. But if the ad load is more reasonable, and the ads are more relevant to consumers, many are willing to watch them in exchange for content-especially if they get a discount. Seventy percent of consumers with three or more subscriptions said they would view advertising to get a new streaming service for a 25 percent reduction in price. Ad-supported streaming services offer a fair exchange of attention for content-a big factor in their popularity. Not only options, but superior options thanks to dynamic advertising, which allows advertisers to serve consumers who are watching the same program with individualized ads based on their profile and data. Additionally, using a platform that combines streaming video with data-driven advertising can enable an efficient market for exchanging personal data for content. Ads provide much-needed revenue for services like the Chinese "big three" that seek to expand into new areas, such as gaming and music. Subscriptions will remain part of the mix for premium content, such as sports and original programs. For other services, providers may have to decide between making them subscription-only or joining an ad-supported aggregator. In both Asia and the United States, advertisers will likely move more of their spending to ad-supported services, attracted by millions of "eyeballs," the ability to target individual consumers, and the certainty that their brands will be attached to professionally produced shows and movies-known quantities in comparison with user-generated content. His identity was changed to avoid reprisals from his employer, since much of his binge-watching occurred at his desk during business hours. For Indians, the popularity of cricket is like that of American football in the United States-huge, with a passionate fan base. There are approximately 1 billion cricket fans worldwide, and 90 percent of them are in India. Tasneem Akolawala, "Cricket World Cup 2019: Hotstar breaks record with 100 million daily active users on India vs. This figure does not include online advertising revenue from consumer-generated content. This could come from services that rely solely on ads for revenue, or from services that combine ad and subscription revenue. This data was analyzed by Deloitte Global to develop global and regional forecasts for 2020. William Chou, Roger Chung, and Taylor Lam, 2018 Deloitte China Mobile Consumer Survey, Deloitte, November 2018. Yin Xiaosheng, Xie Hao, and Shao Meiqi, "Chinese loosen purse strings for content," Xinhua News Agency, August 25, 2019. Keith Noonan, "iQiyi just made a major move into video games," Motley Fool, August 5, 2018. China Internet Watch, "Top mobile apps, app stores in China in H1 2019," August 20, 2019. Yue Wang, "iQiyi is no longer content with being the Netflix of China," Forbes, May 29, 2019. Natalie Walters, "Alibaba building Youku to be the Netflix of China," Motley Fool, April 11, 2019. Gaurav Laghate, "Television remains the choice of the masses even in digital times," Economic Times, July 23, 2018. Gaurav Laghate, "Partnership is name of the game in burgeoning video streaming segment," Economic Times, August 6, 2019. Dolly Mahayan, "How Hotstar is upping its ad-revenue game this Cricket World Cup," Exchange4Media, July 11, 2019. Wall Street sees potential for $1 billion yearly windfall," Variety, June 28, 2019. Hulu: Todd Spangler, "Hulu says 70% of its 82 million viewers are on ad-supported plan," Variety, May 29, 2019. Tubi: Andrew Blustein, "Tubi takes aim at competition in its largest out-of-home campaign," Drum, August 7, 2019. Sahil Patel, "The next front of the streaming wars is the battle for ad-supported programming," Digiday, April 9, 2019. But in a world where overall media and entertainment growth stands at just 4 percent, 2 25 to 30 percent annual growth is impressive, even considering the low absolute base. The signal is clear: Audiobooks and podcasts are outgrowing their "niche" status to emerge as substantive markets in their own right. In the United States, for instance, recorded music revenues grew by 12 percent in 2018; vinyl record revenues 3 Outside these two well-studied markets, data is sparse and the markets themselves more nascent. According to a 2018 survey, 18 percent of American adults said that they listened to an audiobook in the last 12 months, up four percentage points since 2016. Globally, the number of current audiobook consumers almost certainly exceeds half a billion.

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Recently symptoms stiff neck buy rivastigimine 1.5mg cheap, the American Society of Clinical Oncology stated that this strategy is clinically and economically appropriate for patients who are receiving a chemotherapy regimen with a 20% or higher risk of febrile neutropenia symptoms endometriosis rivastigimine 3 mg online. It is recommended that secondary prophylaxis be reserved for patients with chemosensitive cancers where dose reduction may affect disease-free or overall survival medicine 7253 cheap rivastigimine 6 mg with amex. These beneficial effects medications may be administered in which of the following ways cheap rivastigimine 4.5 mg line, however, have not resulted in improved response rates or overall survival. Growth factors should not be used in patients receiving concomitant chemotherapy and radiotherapy, especially if the radiation involves the mediastinum. This reaction is more common after intravenous infusion and consists of dyspnea, facial flushing, hypotension, hypoxia, and tachycardia. The dose for other uses varies, for instance in the setting of peripheral blood stem cell mobilization doses of 10 mcg/kg per day are usually used. At most centers, platelet transfusions are reserved for patients with a platelet count of <10,000 cells/mm3 (<10 Ч 109/L) unless they are actively bleeding, must undergo a surgical procedure, or have documented infections or fever in which the threshold is higher. Unfortunately, oprelvekin is associated with some significant adverse effects, mostly related to fluid retention. Cardiac toxicity, especially tachycardia, and atrial fibrillation and flutter also have been observed. Prophylactic oprelvekin also is significantly more expensive than platelet transfusions. Antifungal therapy may be delivered topically for mild infections (thrush) with clotrimazole troches or nystatin oral suspension. For more severe oral or esophageal fungal infections, systemic treatment with oral fluconazole or intravenous antifungals is indicated. Mucosal damage can occur at any point along the entire length of the gastrointestinal tract. In the lower portion of the gastrointestinal tract, this damage is usually manifested as diarrhea (mild to life-threatening in nature) and abdominal pain. Support with intravenous fluids and electrolyte supplementation should be initiated promptly in severe cases. After infectious causes have been ruled out, diarrhea can safely be treated with antispasmodics such as Lomotil or loperamide. The somatostatin analog octreotide has also been used successfully to treat severe cases of chemotherapy-induced diarrhea; guidelines exist to assist practitioners in treating this toxicity. Common reactions include localized rash, photosensitivity, skin hyperpigmentation, nail changes, and hand­foot syndrome, but can be associated with severe hypersensitivity reactions. Although no clear guidelines exist for the treatment of this rash, patients should be supported based on their presentation. Disruption of the gastrointestinal mucosal barrier may also provide an avenue for systemic microbial invasion. The time course for development and resolution of mucositis often parallels that of neutropenia. Currently, the most effective means of preventing mucositis is through good oral hygiene. Patients who are at high risk for this toxicity (those with poor dentition, high-dose chemotherapy, or radiation therapy involving the oropharynx) should be evaluated by a dentist prior to chemotherapy and should be instructed to rinse their mouths frequently with baking soda and salt water or plain saline rinses during and between courses of chemotherapy. Clinical practice guidelines for the prevention and treatment of cancer therapy-induced mucositis were recently published. In patients undergoing radiation therapy to the head and neck region, chlorhexidine rinses have detrimental effects on the oral mucosa. A better understanding of the pathophysiology of mucositis has resulted in identification of promising new agents to better prevent mucositis. The keratinocyte growth factor palifermin is approved for use in patients receiving high-dose chemoradiotherapy prior to hematopoietic stem cell transplantation. Palifermin is given intravenously at a dose of 60 mcg/kg/day for 3 consecutive days immediately before the initiation of conditioning therapy and then again for 3 days after hematopoietic stem cell transplantation. After mucositis has developed, treatment is mainly supportive, including use of topical or systemic analgesics and oral hygiene (including the rinses described). Severe cases of mucositis may lead to dehydration and require intravenous hydration and pain medications including patient-controlled analgesia pumps. Local infections caused by Candida species and reactivation of herpes simplex viruses are common in these patients. Alopecia from chemotherapy is usually temporary, and the degree of hair loss varies widely. Patients receiving a taxane as part of their chemotherapy regimen are especially prone to total body alopecia. Hair loss usually begins 1 to 2 weeks after chemotherapy, and regrowth may begin before the chemotherapy courses are completed. Cryotherapy (local application of ice) and scalp tourniquets have both been investigated as methods of preventing alopecia. Both techniques produce vasoconstriction, resulting in decreased exposure of hair follicles to the chemotherapy agents. These techniques are not uniformly effective and are contraindicated in patients with cancers that may metastasize to the scalp, such as leukemia and lymphoma. The anthracyclines are the most noto- 2224 rious agents, and the most extensively investigated. The tissue damage may result in prolonged pain, tissue sloughing, infection, and loss of mobility. Prompt initiation of the appropriate interventions is important to minimize morbidity. Unfortunately, most information on extravasation management is anecdotal; few controlled clinical trials have been conducted to determine optimal intervention strategies. The most important method of prevention is good administration technique, but extravasations may occur despite good administration technique. The large veins of the forearm are desirable because if a drug does extravasate, there is adequate soft-tissue coverage to protect crucial structures like nerves and tendons, and joint function is not put at risk. The person administering the vesicant should verify needle stability and adequate blood return after each 1 to 2 mL of drug is injected. Vesicants should not be administered by intravenous infusion unless the patient has a central venous catheter. For extravasation of vesicants, one of the most important interventions is the application of ice packs to the affected area. One exception to this rule is the vinca alkaloids, which are better managed with application of heat. Sodium thiosulfate is used to neutralize nitrogen mustard extravasations, and hyaluronidase (if available) can improve the outcome after extravasation of vinca alkaloids, etoposide, and taxanes. Topical application of dimethyl sulfoxide may be an effective method for managing anthracycline and mitomycin C extravasations. Acute myelogenous leukemia or myelodysplastic syndrome has been reported following successful treatment of Hodgkin and non-Hodgkin lymphoma, acute leukemias, multiple myeloma, breast cancer, and advanced ovarian cancer. For curable cancers, the relatively small risk for occurrence of secondary malignancies is far outweighed by the benefits of survival in large numbers of patients. However, for cancers such as ovarian cancer, the risk of leukemia is not offset by improved survival in patients treated with chemotherapy. The issue of secondary malignancies is of particular concern in patients receiving adjuvant chemotherapy. As with the late complication of infertility, the anticancer agents primarily associated with secondary cancers are the alkylating agents. Etoposide, teniposide, radionucleotides, and the anthracyclines also are linked to secondary leukemias. Solid tumors as secondary malignancies occur more commonly after treatment with radiation than with chemotherapy. The gonadal toxicities of chemotherapy have not received much attention in the past because they are not life-threatening. High rates of fertility deficits and sexual dysfunction have been noted for both men and women. The recovery of spermatogenesis after completion of chemotherapy is unpredictable. Men receiving combination chemotherapy appear to sustain more long-lasting adverse effects on fertility than do men receiving single-agent therapy.

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Syndromes

  • Diabetes
  • Platelet aggregation test
  • Removing blood or blood clots if they are raising pressure inside the skull and causing herniation
  • Headache
  • Antiphospholipid antibodies
  • How to hold your head
  • Complications of treatment (radiation therapy or chemotherapy)
  • Sjogren syndrome
  • Chest x-ray

Unfortunately medicine 44390 cheap rivastigimine 1.5 mg without a prescription, many wearers had sensitivity reactions medicine 3x a day cheap rivastigimine 3 mg mastercard, and these products and chemical disinfection fell into disfavor symptoms strep throat cheap rivastigimine 4.5mg visa. The introduction of hydrogen peroxide systems for chemical disinfection revitalized this method of disinfection medicine hollywood undead buy discount rivastigimine 1.5 mg on line. It is thought that the free radicals chemically released from the peroxide react with the cell wall of the microorganisms, and the bubbling action of the peroxide is thought to promote removal of any remaining debris on the lens. To prevent eye irritation from residual peroxide after disinfection, it is necessary that the lenses be exposed to one of three types of neutralizing agents: the catalytic type (an enzyme catalase or a platinum disk), the reactive type (such as sodium pyruvate or sodium thiosulfate), or the dilution­elution type. Soaking and Storage Solutions Hard lenses are placed in a soaking solution once they are removed from the eye. Soaking solutions contain a sufficient concentration of disinfecting agent, usually 0. Overnight soaking is advantageous because it keeps the lenses wet and the prolonged contact time helps to loosen deposits that remain after routine cleaning. Wetting Solutions Wetting solutions contain surfactants to facilitate hydration of the hydrophobic lens surface and enable the tears to spread evenly across the lens by providing it with temporary hydrophilic qualities. These solutions also provide a cushion between the lens and the cornea and eyelid. Typical ingredients include a viscosity-increasing agent, such as hydroxyethyl cellulose; a wetting agent, such as polyvinyl alcohol; preservatives, such as benzalkonium chloride or edetate disodium; and buffering agents and salts to adjust the pH and maintain tonicity. While they are characterized by ease of use, combination products may lower the effectiveness of cleaning if the concentration of cleaning solution is too low to adequately remove debris from the lens. These combination solutions should be reserved for wearers who have a demonstrated need for simplification of lens care. One of two cleaning methods, either hand washing or mechanical washing, may be used. In the first method, the lens may be cleaned by holding the concave side up in the palm of the hand. The lens should not be held between the fingers because the flexibility of the lens may allow it to warp or turn inside out. Mechanical washing is advantageous because the possibility of the lens turning inside out or warping during cleaning is minimized. After overnight soaking, the lens is rubbed with fresh wetting or soaking solution and inserted into the eye. To facilitate removal of stubborn protein deposits, weekly cleaning with enzymatic cleaners is recommended. Clinical Considerations in the Use of Contact Lenses Although most medicated eyedrops may be used in conjunction with the wearing of contact lenses, some caution should be exercised and drug-specific information used, particularly with soft contact lenses, because this type of lens can absorb certain topical drugs and affect bioavailability (13, 15). Use of ophthalmic suspensions and ophthalmic ointments by contact lens wearers presents some difficulties. The drug particles in ophthalmic suspensions can build up between the cornea and the contact lens, causing discomfort and other undesired effects. Thus, an alternative dosage form, such as an ophthalmic solution, may be prescribed or lens wearing deferred until therapy is complete. Some drugs administered by various routes of administration for systemic effects can find their way to the tears and produce drug­contact lens interactions. In addition, drugs that cause ocular side effects have the potential to interfere with contact lens use. Isotretinoin, prescribed for severe, recalcitrant acne, can induce marked dryness of the eye and may interfere with the use of contact lenses during therapy. Use of ophthalmic vasoconstrictors occasionally causes dilation of the pupil, especially in people who wear contact lenses or whose cornea is abraded. Although this effect lasts only 1 to 4 hours and is not clinically significant, some patients have expressed concern. The following guidelines should be used by pharmacists in counseling patients: Contact lens wearers should wash their hands thoroughly with a nonabrasive, noncosmetic soap before and after handling lenses. Wearers should not rub the eyes when the lenses are in place, and if irritation develops, the lenses should be removed until these symptoms subside. Only contact lens care products specifically recommended for the type of lens worn should be used. Also, to avoid differences between products of different manufacturers, it is preferable to use solutions made by a single manufacturer. Cleaning and storing lenses should be performed in the specific solution for that purpose. The patient should be instructed to discard cleansers and other lens care products if the labeled expiration date is exceeded. Lenses should not be stored in tap water, nor should saliva be used to help reinsert a lens into the eye. When handling a contact lens over the sink, the drain should be covered or closed to prevent the loss of the lens. Similarly, the lens should be inspected for any particulate matter, particles, warpage, and/or discoloration. When cleaning a lens, the patient should be instructed to clean it back and forth and not in a circular direction. To avoid the "left-lens syndrome," the patient should be instructed to clean the second lens as thoroughly as the first lens. Oftentimes, the right lens is removed and cleaned first and the second less thoroughly, which will result in more deposits after cleaning. As appropriate, contact lens users should be counseled with regard to cosmetic use. It is prudent to purchase makeup in the smallest container, because the longer a container is open and the more its contents are used, the greater the likelihood of bacterial contamination. Mascara and pearlized eye shadow should be avoided by women wearing hard lenses because particles of these products can get into the eye and cause irritation, with corneal damage a possibility. Aerosol hairsprays should be used before the lens is inserted and preferably applied in another room, since airborne particles may attach to the lens during insertion and cause irritation. Lenses should be inserted before makeup application because oily substances on the fingertips can smudge the lenses when they are handled. If pain is present, it may be a sign of ill-fitting lenses, corneal abrasion, or other medical condition, and the patient should be advised to consult his or her ophthalmologist (15). Hard or soft contact lenses may occasionally cause superficial corneal changes, which may be painless and not evident to the patient. Thus, it is important that all contact lens wearers have their eyes examined regularly to make certain that no damage has occurred. The antimicrobial preservatives are the same as those used in ophthalmic solutions. The concentration of adrenergic agent in most nasal decongestant solutions is quite low, ranging from about 0. Certain commercial solutions are available in adult and pediatric strengths, the pediatric strength being approximately half of the adult strength. Nasal decongestant solutions are employed in the treatment of rhinitis of the common cold, for vasomotor and allergic rhinitis including hay fever, and for sinusitis. Frequent or prolonged use may lead to chronic edema of the nasal mucosa, that is, rhinitis medicamentosa, aggravating the symptom that they are intended to relieve. Thus, they are best used for short periods (no longer than 3 to 5 days), and the patient should be advised not to exceed the recommended dosage and frequency of use. The easiest but least comfortable approach to treat rebound congestion is complete withdrawal of the topical vasoconstrictor. Unfortunately, this approach will promptly result in bilateral vasodilation with almost total nasal obstruction. Once the rebound congestion subsides in the drug-free nostril, after about 1 to 2 weeks, a total withdrawal is instituted. Another approach is substitution of a topical saline solution or spray for the topical vasoconstrictor. This keeps the nasal mucosa moist and provides psychologic assistance to patients who are dependent on placing medication into their nostrils.

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