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Thomas J Smith, M.D.

  • The Harry J. Duffey Family Professor of Palliative Medicine
  • Professor of Oncology

https://www.hopkinsmedicine.org/profiles/results/directory/profile/8283165/thomas-smith

Psoriasis: Improvement of genital lesions seen with application of topical steroids and emollients insomnia jobs order modafinil 100 mg amex, dermatologic evaluation necessary insomnia 7 months pregnant generic 200 mg modafinil with amex. Goal of therapy to remove lesion; total eradication of human papilloma virus most often impossible sleep aid hormone generic 100mg modafinil with visa. Electrocautery or laser therapy necessary for large lesions not responding to topical agents; liquid nitrogen also used as cryotherapy insomnia during period order 100mg modafinil with mastercard. Serum creatinine to assess baseline kidney function; continue evaluation if elevated by imaging (ultrasound), etc. Nifedipine improves pain, and decreases the frequency of pain episodes, use of oral analgesics, and emergency room visits. Improvement in biliary pain and recurrent pancreatitis can be achieved in 50 to 60 percent of patients treated by surgical sphincterotomy. It is controversial whether Blastocystis hominis is a pathogen, and it is found frequently in absence of symptoms. Other tests: none differential diagnosis Any cause of mild chronic diarrhea management What to Do First Determine presence of symptoms. Blastocystis Hominis Infection General Measures None Blastomyces Dermatitidis 243 specific therapy Indications A symptomatic patient in whom no other cause of diarrhea can be found (after proper search) can be treated empirically (no treatment trials yet published). Treatment Options Metronidazole for 10 days Iodoquinol for 20 days Side Effects & Complications As for amebiasis, giardiasis Contraindications to treatment: absolute: allergy to medications Contraindications to treatment: relative: asymptomatic patient, and some feel no one should be treated follow-up Routine If treated, stools can be re-examined. Lawrence River area of New York and Canada Middle-aged men with outdoor occupations that expose them to soil may be at highest risk. Signs & Symptoms Blastomycosis is a systemic disease with a wide variety of pulmonary and extrapulmonary manifestations. Baseline bone densitometry and follow-up evaluation should be performed and calcium and vitamin D along with a bisphosphonate is advised for patients on 5 mg/d or higher doses for >3 months. With candidemia, blood cultures should be obtained every other day until negative. With candidemia, once blood cultures are clear, obtain ophthalmologic evaluation to rule out candida chorioretinitis or endophthalmitis. Underlying condition: sepsis, renal failure, known heart/lung disease, toxic exposure. If foreign body aspiration suspected, tonguejaw lift and finger sweep, followed by Heimlich maneuver. Elbows locked, 11 2 to 2 excur/ sions, 100 compression/min Defibrillation: attach monitor/defibrillator. Consider allowing family member presence during resuscitative efforts (shown to ease the grieving process). Training practice of lifesaving procedures on newly dead patients only under defined educational programs Successful Resuscitation Survival to discharge after an in-hospital cardiac arrest usually <15% Prognostic factors: most important factor is time of resuscitative efforts. Unclear if therapy affects resolution of retinitis, hepatosplenic granulomatous disease, osteitis or encephalopathy, but many would treat with doxycyline or erythromycin with or without rifampin follow-up Spontaneous resolution may be slow and intermittent clinical assessment is indicated, particularly when the diagnosis is clinical. Syncope in the presence of bifascicular block: increased incidence of sudden cardiac death. Use only for serious menopausal symptoms, not for prevention of heart attack or stroke. Guidelines for the diagnosis and treatment of chronic heart failure: executive summary (update 2005): the Task Force for the Diagnosis and Treatment of Chronic Heart Failure of the European Society of Cardiology. Thiazides or metolazone alone in mild fluid retention, loop diuretics in most patients (mild-severe); metolazone and loop diuretic in severe cases. Side Effects and Complications: renal failure, thrombocytopenia, orthostatic hypotension, dizziness, dry mouth, headache, nausea/vomiting, dyspepsia, impotence, rash, hypokalemia, muscle cramps, ototoxicity. Advise patients of possible early side effects which do not generally prevent long-time use. Side effects may occur at any level, though more frequent >2 ng/mL and in elderly. Improves morbidity and mortality in advanced heart failure patients (spironolactone) and in post-myocardial infarction heart failure patients (eplerenone). May consider Amlodipine, which has demonstrated no adverse effect on survival (also perhaps felodipine). Class I agents (quinidine, procainamide, flecainide, encainide) increase risk of death. May consider amiodarone for atrial arrhythmias, but not for general use to prevent death/sudden death. Chronic: Infection, inappropriate pacing, pacemaker syndrome, system failure (leads, generator). Educate patient about pathophysiology of heart failure and reason for medications (improves outcomes and compliance). Routine Follow-up at least every 6 months Improved outcomes noted when followed by cardiologist, heart fail- ure specialist. Signs & Symptoms May be asymptomatic; symptoms usual when estimated glomerular filtration rate 25 mL/min/1. If still elevated, administer active vitamin D such as calcitriol or paricalcitriol. Treat hemoglobin <11 g/dl with subcutaneous erythropoietin or dar- bepoietin subcutaneously along with oral or intravenous iron therapy. Goals: urine albumin/creatinine ratio <300 mg/g, urine protein/creatinine <200 mg/g. More potent second-generation abl kinase inhibitors are actively being investigated in the clinic now. Timing of transplant, especially for young patients with matched related donors, remains controversial. Most experts suggest initial trial of imatinib, but move to transplant for patients with suboptimal response to imatinib (failure to achieve a complete hematologic response after 3 months, or failure to achieve any significant cytogenetic response after 6 months, or failure to achieve a major cytogenetic response after 1 year), or development of imatinib resistance. Can compromise the ability of a patient to be transplanted and therefore not used for primary therapy. Evidence for imatinib resistance or disease acceleration should prompt rapid intervention with increased dose of imatinib, second-generation abl kinase inhibitor, or transplantation for those who are candidates. It is unknown if such patients are "clinically cured," as follow-up times are still relatively short. Such patients may be salvaged with higher doses of imatinib, secondgeneration abl kinase inhibitors, use of the above-mentioned cytostatic or cytotoxic agents alone or in combination, or preferably stem cell transplant if the patient is still in chronic phase of disease. Prognosis is poor for patients who cannot be transplanted and who develop abl kinase inhibitor resistance. Patients who relapse after allogeneic stem cell transplantation can be salvaged by donor lymphocyte infusions. Vaccines and other forms of immunotherapy are under investigation and may prove useful.

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The Resilient Organization: A Meta-analysis of the Effect of Communication on Team Diversity and Team Performance Authors insomnia dallas discount modafinil 200mg without a prescription. Creating an Engaged Workforce: the Impact of Authentic Leadership insomnia zoloft temporary generic modafinil 100mg online, Transparent Organizational Communication sleep aid games buy discount modafinil 100 mg on line, and Work-Life Enrichment sleep aid belsomra proven modafinil 200 mg. Effects of Group Communication Cohesion of Staff and Cluster Analysis in a Multi Campus University. Examining Project Commitment in Cross-Functional Teams; Antecedents and Relationship with Team Performance Examining Project Commitment in Cross-Functional Teams; Antecedents and Relationship with Team Performance. The Influence of Intrinsic and Extrinsic Rewards on Employee Results; An Empirical Analysis in Turkish Manufacturing Industry. The portrait of the use of the National Health Insurance can be seen from the number of visits which increase each year. The increase in patient visits at local health center makes the local health center employees overwhelmed with a lot of tasks. Based on the initial survey at the Keputih Health Center, it was found that the burnout rate of employees in 2018 was 50. The purpose of this study was to analyze the effect of burnout on employee job satisfaction in 9 local health centers in Surabaya. The population of this research is all employees of the Surabaya City Health Center who provide services for patients directly every day. The results showed that the likelihood of respondents with high burnout would have a higher job satisfaction 5. The conclusion is that low burnout will leads to the possibility of higher job satisfaction. Indonesia has taken a significant step by using the National Health Insurance which is an amalgaation of various forms of health insurance which have been applied previously. The portrait of the utilization of the National Health Insurance can be seen from the number of visits which increase every year. The implementation of National Health Insurance in all regions, including the rempte areas and borders, must be balanced with equitable distribution of human resources and the fulfillment of the availability of health care facilities2. Average Monthly Patient Visits in 20162018 at Keputih Health Center Surabaya the Surabaya city has 63 health centers in total which spread all over the region. The national health 1280Indian Journal of Public Health Research & Development, March 2020, Vol. The Gatekeeper means it is the first level of health service facility and place of contact for patients that can be used to reduce the possibility of patient referrals to an advanced health facilities and it is function as an effort to control quality and costs3. The increase in the average visit of these patients consequently increases the workload of employees in the local health centers which leads to possibility of burnout. Burnout is a prolonged response to chronic emotional and interpersonal stressors on the job, and is defined by the three dimensions of exhaustion, cynicism, and inefficacy. Exhaustion is the central quality of burnout and the most obvious manifestation of this complex syndrome. Depersonalization is an attempt to put distance between oneself and service recipients by actively ignoring the qualities that make them unique and engaging people. The relationship of inefficacy (reduced personal accomplishment) to the other two aspects of burnout is somewhat more complex, It is difficult to gain a sense of accomplishment when feeling exhausted or when helping people toward whom one is indifferent. The lack of efficacy seems to arise more clearly from a lack of relevant resources, whereas exhaustion and cynicism emerge from the presence of work overload and social conflict4. Burnout Perception of Employees at Keputih Health Center Surabaya Statement Physical exhaustion at the end of the work day. Average Disagree n % Agree n % employees tend to experience physical fatigue and over worked. Negative and unfavourable attitudes towards the job indicate job dissatisfaction5. Employee Satisfaction in Keputih Health Center Surabaya Statement Praise for work you have done. We can also see that the employees feel dissatisfied with the praise or reward for the work they done; and they also not satisfied with the opportunity offered to improve; and not as well satisfied with the work system at the Local health center. Overall, the initial survey at the health center in Keputih resulted in a good level job satisfaction but with a high perception of burnout. Therefore this study was conducted to learn about the effect of burnout on the work satisfaction of employees at the Surabaya city health center. Material and Method this type of this research is quantitative and the design is observational analytic. The data collection technique is the cross sectional with population of all employees of the Surabaya City Health Center who provide services to patients directly every day. The inclusion criteria in this study are health center employees who provide services for patients directly every day. While the exclusion criteria in this study are employees who provide services indirectly to patients and employees who provide services directly to patients but not every day. It can also be concluded that the average perception of burnout experienced by the employees in Keputih Health Center is 50. The burnout level was measured through the 1981 Maslach Burnout syndrome Inventory questionnaire7. The results of this research are not able to be generalized due to the method of sampling is not random therefore the results of the study will illustrate the extent of its influence but not in its significance. Findings And Discussion Identification of Employee Burnout Level in 9 Surabaya City Health Centers: Burnout has 3 dimensions, namely Exhaustion, Depersonalization, and Personal Accomplishment. The following is an identification of employee burnout levels based on 3 dimensions of burnout. Identification of Employee Burnout Levels in 9 Surabaya City Health Centers Percentage Distribution of Score Questions n Exhaustion Emotional drain Physical exhaustion at the end of the work day. The average value shows that respondents feel satisfied with their work both in terms of salary, relationship to superiors and subordinates, work environment conditions and so on. Test Result of the Effect of Burnout on Job Satisfaction: the following is a 3-dimensional relationship of burnout on employee job satisfaction Table 5. Hasildariidentifikasitingkat burnout dantingkatkepuasankaryawankemudian di ujimenggunakanaplikasi statistic untukmelihatpengaruh burnout terhadapkepuasankerja. Soedarso Pontianak Hospital which resulted that there was a significant negative relationship between job satisfaction and burnout on nurses (r = -0. The results of this research are also in line with the research of Maslach, Schaufeli, and Leiter (2001) which stated that for people who stay on the job, burnout leads to lower productivity and effectiveness at work. Consequently, it is associated with decreased job satisfaction and a reduced commitment to the job or organization. People are experiencing burnout will have a negative impact on their colleagues, both by causing greater personal conflict and by disrupting job tasks4. Based on the result it can be learned that respondents with low depersonalization have a high likelihood of better job satisfaction. Respondents tend to be comfortable and able to place themselves as a service provider. The multivariate regression analysis showed a significant predictor of depersonalization, namely using knowledge and skills in the workplace10. Based on these results it can be learned that the respondents who have a low total burnout have the possibility experience higher job satisfaction. These results are in line with the research conducted by Andarini (2018) where Burnout syndrome has a Conclusions Based on the analysis of the effect of burnout on job satisfaction, it is found that when the exhaustion; 1284Indian Journal of Public Health Research & Development, March 2020, Vol. Based on the results the author recommends that Local health center calculate the workload of each employee so that workload adjustments can be made for employees. Besides, local health center can take the employees for outbound at least once a year to improve interpersonal relations both between employees to superiors and fellow employees and to relieve boredom by the many demands of the work. Analysis of Factor Causing Burnout Syndrome and Job Satisfaction in Gersik Petrokimia Hospitals [Internet]. Preeclampsia is a specific condition in pregnant women over 20 weeks characterized by placental dysfunction. The case of preeclampsia in Kenjeran Subdistrict Community Health Center (Puskesmas) is one of the highest in Surabaya. The population of this study were all preeclampsia mothers in Kenjeran Subdistrict Puskesmas. It is recommended to improve and maintain family support as a social factor for preeclampsia mothers to immediately make a decision to choose a place of delivery. As well as the need for approaches to local customs and culture by health workers to be easily accepted by the community.

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Advanced-stage disease is treated palliatively with single agents (cisplatin insomnia long-term effects purchase 100 mg modafinil otc, irinotecan insomnia 10 code buy discount modafinil 200mg, ifosfamide) sleep aid app for iphone 100 mg modafinil overnight delivery. Lymphatic spread is assessed surgically; it is present in only 10% of those with Gleason grade 5 or lower and in 70% of those with grade 9 or 10 sleep aid puppy modafinil 200mg sale. Prostate Carcinoma For pts with stages A through C disease, surgery (radical retropubic prostatectomy) and radiation therapy (conformal 3-dimensional fields) are said to have similar outcomes; however, most pts are treated surgically. Mitoxantrone, estramustine, and taxanes appear to be active single agents, and combinations of drugs are being tested. Prostate Cancer Prevention Finasteride has been shown to reduce the incidence of prostate cancer by 25%, but no effect on overall survival has been seen with limited follow-up. Clinical Presentation Pts may present with fatigue, weight loss, pain, bleeding, abdominal swelling, subcutaneous masses, and lymphadenopathy. Localizing symptoms, a history of carcinogen exposure, or a history of fulguration of skin lesion may direct some clinical testing; however, the careful light microscopic, ultrastructural, immunologic, karyotypic, and molecular biologic examination of adequate volumes of tumor tissue is the most important feature of the diagnostic workup in the absence of suspicious findings on history and physical exam (Table 80-1). Limited sites of involvement and neuroendocrine histology are favorable prognostic factors. All-purpose chemotherapy regimens rarely produce responses but always produce toxicity. With severe hyponatremia (<115 meq/L) or in the setting of mental status changes, normal saline infusion plus furosemide may be required; rate of correction should be <1 meq/L per hour to prevent complications. A biopsy of affected nervous system tissue may be useful to rule out other disorders. Patients with additional antibodies to other Ma proteins are men or women with a variety of solid tumors. Neuropathies occurring at late stages of cancer or with lymphoma are usually due to axonal degeneration of unclear etiology. Paraneoplastic Neurologic Disorders these disorders in general respond poorly to therapy. The traditional detection methods of microscopy and culture are timeconsuming and are increasingly being replaced by nucleic acid probe assays. Acid-fast stains are useful for organisms that retain carbol fuchsin dye after acid/organic solvation. After proliferation of viral particles, cells are examined for cytopathic effects or immunofluorescent studies are performed to detect viral antigens. To predict sensitivity (typically of viruses) to chemotherapeutic agents Probes are available for directly detecting various pathogens. Whole blood Whole blood Blood, Isolator (lysis centrifugation) Whole blood 10 mL in each of 2 bottles for adults and children; 5 mL, if possible, in aerobic bottles for infants; less for neonates 10 mL in each of 2 bottles, as for routine blood cultures, or in Isolator tube requested from laboratory 10 mL See below. Stool Stool for routine culture; stool for Salmonella, Shigella, and Campylobacter Stool for Yersinia, Escherichia coli O157 Stool for Aeromonas and Plesiomonas Rectal swab or (preferably) fresh, randomly collected stool Fresh, randomly collected stool Fresh, randomly collected stool 1 g of stool or 2 rectal swabs Plastic-coated cardboard cup or plastic cup with tightfitting lid. Limitations: Stool should not be cultured for these organisms unless also cultured for other enteric pathogens. Culturette swab or similar transport system or sterile tube with tight-fitting screw cap. Collection: Abscess contents or other fluids should be collected in a syringe (rather than with a swab) when possible to provide an adequate sample volume and an anaerobic environment. Sputum, tissue, urine, body fluids 1 mL or as specified above for individual listing of specimens. Special considerations: There is no more important clinical microbiology test than the detection of blood-borne pathogens. Fecal samples should be collected before the ingestion of barium or other contrast agents and before treatment with antidiarrheal agents or antacids; these substances alter fecal consistency and interfere with microscopic detection of parasites. Microscopic examination is not complete until direct wet mounts have been evaluated and concentration techniques as well as permanent stains applied. Sampling of duodenal contents may be needed to detect Giardia lamblia, Cryptosporidium, and Strongyloides larvae. The major mechanisms of resistance used by bacteria are drug inactivation, alteration or overproduction of the antibacterial target, acquisition of a new drug-insensitive target, decreased permeability to the agent, failure to convert an inactive prodrug to its active derivative, and active efflux of the agent. Evidence-based practice guidelines for most infections are available from the Infectious Diseases Society of America ( The rates are consistent with those reported by the National Nosocomial Infections Surveillance System (Am J Infect Control 32:470, 2004). Efforts to lower infection risks have been challenged by the growing numbers of immunocompromised pts, antibiotic-resistant bacteria, fungal and viral superinfections, and invasive procedures and devices. Hospital infection-control programs focus primarily on infections associated with the greatest morbidity or the highest costs. Other measures include identifying and eradicating reservoirs of infection and minimizing use of invasive procedures and catheters. Hand hygiene and use of gloves are central components of standard precautions; in certain cases, masks, eye protection, and gowns are used as well. Lower tract symptoms, such as dysuria, are unreliable as markers of infection in catheterized pts. In men, condom catheters-unless carefully maintained-are as strongly associated with infection as indwelling catheters. Risk factors include events that increase colonization with potential pathogens, such as prior antibiotic use, contaminated ventilator equipment, or increased gastric pH; events that increase risk of aspiration, such as nasogastric or endotracheal intubation or decreased level of consciousness; and conditions that compromise host defense mechanisms in the lung, such as chronic obstructive pulmonary disease. Diagnosis depends on clinical criteria such as fever, leukocytosis, purulent secretions, and new or changing pulmonary infiltrates on chest x-ray. Prevention of Surgical-Site Infections Administer prophylactic antibiotics within 1 h before surgery; discontinue within 24 h. Limit any hair removal to the time of surgery; use clippers or do not remove hair at all. Efforts at prevention should focus on meticulous aseptic care of respirator equipment and the interventions listed in Table 85-1. These infections often become evident after pts have left the hospital; thus it is difficult to assess the true incidence. In rapidly progressing postoperative infections, group A streptococcal or clostridial etiologies should be considered. The diagnosis is confirmed by isolation of the same bacteria from peripheral blood cultures and from semiquantitative or quantitative cultures of samples from the vascular catheter tip. If salvage of the catheter is attempted, the "antibiotic lock" technique (instillation of concentrated antibiotic solution into the catheter lumen along with systemic antibiotic administration) may be used. If the catheter is changed over a guidewire and cultures of the removed catheter tip are positive, the catheter should be moved to a new site. Norovirus causes nosocomial outbreaks of diarrheal syndromes in which nausea and vomiting are prominent aspects. Contact precautions may need to be augmented by environmental cleaning and active exclusion of ill staff and visitors. Bioterrorism preparedness: Education, effective systems of internal and external communication, and risk assessment capabilities are key features. Cellulitis caused by streptococci, staphylococci, Escherichia coli, Pseudomonas, or fungi 2. Pts have fever, right lower quadrant tenderness, and diarrhea that is often bloody. Splenectomized pts and those with hypogammaglobulinemia are also at risk for infection with encapsulated bacteria such as Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis. Encephalitis can develop in pts receiving high-dose cytotoxic treatment or chemotherapy that affects T cell function. Brain masses: Consider Nocardia, Cryptococcus, Aspergillus, and Toxoplasma gondii. Outpatients who are expected to remain neutropenic for <10 days and who have no concurrent medical problems (such as hypotension, pulmonary compromise, or abdominal pain) can be classified as low-risk and treated with a broad-spectrum oral regimen.

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All 3 drugs may cause mild intestinal symptoms in small minor- ity insomnia quote fight club modafinil 200mg otc, and pyrantel pamoate rarely causes headache xpn sleep aid purchase modafinil 100 mg online, dizziness insomnia opiate withdrawal cheap 100mg modafinil fast delivery, or rash insomnia 5 order modafinil 100 mg fast delivery. Contraindications to treatment: absolute: none Contraindications to treatment: relative: asymptomatic adult not with children follow-up Routine No tests necessary after treatment. If symptoms or visible worms return, retreat entire household and enforce general hygienic measures. Individual serotypes may be most frequently associated with particular syndromes but considerable overlap in clinical manifestations. Most common: nonspecific febrile illness Respiratory: common cold, pharyngitis, herpangina (sore throat with papulovesicular pharyngeal lesions on erythematous base), pneumonia, pleurodynia Hand, Foot and Mouth; often associated with coxsackie A16 but other serotypes can be involved, mild illness associated with sore throat, fever, scattered vesicular lesions on pharynx/lips and grayish vesicles on hands and feet Gastrointestinal: vomiting, diarrhea, abdominal pain, occasionally hepatitis Acute hemorrhagic conjunctivitis Cardiac: myocarditis; clinical symptoms dependent on region and extent of cardiac involvement, often with palpitations, chest Enteroviruses pain, and have history of preceding illness. The body site where enterovirus is detected is important for interpretation to differentiate enterovirus colonization versus enterovirus-associated disease. Note that enterovirus is present in stool for weeks (and sometimes months) after initial infection. Signs & Symptoms Erysipelas Usually facial 544 Erysipelas and Cellulitis Sharply marginated warm, tender, erythematous, edematous, Fever, often to 102 degrees F Vesicles or bullae may occur on the surface. Most often on the extremities Evidence of onychomycosis is frequent and may represent the Less well demarcated than erysipelas, but otherwise the findings are identical Perianal cellulites indurated plaque Cellulitis site of entry for the bacteria. Usually in young children May precede a flare of guttate psoriasis tests Laboratory Basic blood studies: Leukocytosis is frequent. Biopsy is not necessary, but reveals edema, dilated capillaries, and diffuse neutrophilic infiltration. Cultures may be obtained by needle aspiration or biopsy blood cultures may reveal pathologic bacteria Confirmatory Tests Diagnosis is clinical. Erythema multiforme minor Erythema Multiforme Major 547 Patient does not appear ill (no systemic involvement); targe toid lesions present, but are classic targets and typically on extremities; only one mucosal surface sometimes affected (oral) Staphylococcal scalded skin syndrome Occurs primarily in children Rash associated with nasopharyngeal infection, generalized large, flaccid superficial bullae, sparing of mucous membranes Viral exanthem Morbilliform eruption; no target lesions Vasculitis Acute generalized exanthematous pustulosis management What to Do First Discontinue any possible causative agents. Intralesional injection of triamcinolone acetonide 550 Erythema Nodosum Esophageal Cancer Predinsone for severe cases Immunosuppressives may be used for recurrent or chronic, severe disease. History of accidental (usually in children) or deliberate (suicidal) ingestion of liquid or crystalline alkali (drain cleaners, etc. Endoscopic injection of intralesional corticosteroids (triamcinolone 40 mg) increases the interval between dilations. These patients should be monitored closely for signs of deterioration that warrant emergency surgery with possible esophagectomy and colonic or jejunal interposition. Society guidelines recommend endoscopic surveillance every 3 years or more frequently if dysplasia is present. Some case-control studies have suggested improved survival if esophageal adenocarcinoma is detected via a surveillance program. Barium swallow may reveal tertiary contractions (described as "rosary bead" or "corkscrew" esophagus); however, radiographic studies may be entirely normal. In cases of vigorous achalasia, the simultaneous esophageal contractions have higher amplitudes. Treatment Options Calcium channel blockers: relieve chest pain and dysphagia Two tricyclic antidepressants, trazodone and imipramine also effec- tive in relieving chest pain; sublingual or oral nitrates, and anticholinergics may also be used Hot water improves esophageal clearance and decreases the amplitude and duration of esophageal body contractions. In severe cases, pneumatic dilatation, or an extended myotomy should be considered. It is important that biopsies are occasionally repeated to rule out cutaneous lymphoma, even if they are initially inconclusive. If related to medication, withdrawal and therapy with appropriate measures usually leads to resolution. Lash loss, a pearly, cavitated border, or a unilateral chronic ulceration requires biopsy. Polydipsia and polyuria Children present with failure to thrive, short stature and rickets. Morning sedation, weight gain, dry mouth, constipation are most common side effects. Signs & Symptoms Lymphatic filariasis: Many patients have no symptoms Recurrent lymphadenitis with retrograde lymphangitis, gener- ally from groin down thigh or to scrotum, or from axillary nodes down arm Hydrocele In late stages, chronic edema of leg, arm or scrotum, chyluria Loa loa: early stage (usually seen in expatriates): arthralgias, myalgias, mild fatigue, urticaria or other migratory rash, recurrent edematous non-tender swellings on extremities (Calabar swellings), migration of worm across conjunctiva or eyelid, or found in small removed nodule Late, chronic stage: same as above but with less arthralgia, myalgia, and fatigue. In Africans with chronic infections, symptoms are mainly migrating worms and Calabar swellings. Onchocerciasis: light infections: no symptoms Moderate to heavy infections: varying degrees of rash, pruritus, nodules around pelvic girdle and waist (in Africa) or head and neck (W. Later one sees blindness (corneal scarring), enlarged inguinal nodes, and loss of elasticity of skin. Either run 5cc through micropore filter to see microfilariae, or mix with formalin, spin and examine for microfilariae (Knott concentration test). Onchocerciasis: remove nodule and examine for adult Examine small punch biopsy of skin (using a scleral punch, or worms scalpel to remove small shaving that includes the dermal papillae) from calves and upper buttocks in African cases, and shoulders and scapular areas in W. Other tests: Lymphatic filariasis: ultrasound of hydrocele or dilated lymph channels in groin may show motile adult worms. Loa loa: In light cases: other causes of urticaria, arthralgias, collagen vascular diseases Onchocerciasis: Almost any cause of itching and nonspecific rash. General Measures Symptomatic treatment of pruritus, edema, cellulitis, if present specific therapy Indications Treatment of light infections in any filariasis is optional. Ivermectin: allergic reactions (due to parasite death) are frequent early in treatment, but generally not severe, and respond to steroids. Contraindications to treatment: absolute: diethlycarbamazine should never be used in onchocerciasis where there is eye involvement. Patients with heavy loa loa should receive even more cautious gradations of dosage. Routine Lymphatic filariasis and loa loa: clinical follow-up, as well as follow- ing eosinophil count and blood examinations. Lymph channel damage prior to treatment will have limited improvement and edema may persist. Streptococcal infections may recur, and sometimes chronic penicillin coverage is needed. Loa loa: heavily infected patients can get an encephalitis during treatment; they need to be treated slowly and watched. Onchocerciasis: Eye disease may improve some, but corneal scarring will not reverse. Clinical manifestations of Folate/cobalamin deficiency are similar (with notable exceptions). Clinical Presentations: Pancytopenia with megaloblastic marrow; congestive heart failure; beefy-red tongue; melanin pigmentation, premature graying; infertility/sterility Neuropsychiatric presentation (subacute combined degeneration involving posterior, pyramidal, spinocerebellar, and spinothalamic tracts and secondarily peripheral nerves) unique to cobalamin deficiency. Dorsal tract involved earliest in >70% with paresthesias/ataxia, diminished vibration (256 cps) and proprioception sense. In developing countries, however, cobalamin deficiency can present with florid pancytopenia, mild hepatosplenomegaly, fever, and thrombocytopenia, with the neuropsychiatric syndrome manifesting later. Note: Nonvegetarians who eat small portions of meat infrequently can have low cobalamin intakes comparable to vegetarians/ vegans. Stage I test result, >8% of orally absorbed (crystalline) [57Co] cobalamin excreted in urine in 24 hours. If >8% excretion, result c/w bacterial usurpation; if still <8% excretion, cobalamin malabsorption localized to ileal cause.

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Keywords: Prevalence sleep aid trazodone discount 200 mg modafinil mastercard, dental caries insomnia gr forum buy modafinil 100 mg on-line, parents education level Corresponding Author: Dr sleep aid melatonin cheap modafinil 200 mg overnight delivery. Lilies Anggarwati Astuti Department of Periodontology insomnia korean version cheap modafinil 200mg online, Faculty of Dentistry, University of Muslim Indonesia, Pajonga Dg Ngalle St no. The results of 2132Indian Journal of Public Health Research & Development, March 2020, Vol. Generally, school-age children like to consume sweet foods and beverages that generally contain sucrose sugar type, which is one of the factors that cause dental caries. These diseases cause tooth cavities Dental caries is spread around the world, where the disease can not be healed by itself. The structure of tooth elements and the factors that affect the occurrence of caries teeth should be known, if we want to know how the process of dental caries. Dental caries can be experienced by everyone and can occur on one or more teeth surfaces and may extend to the deeper parts of the tooth, for example from enamel to dentin or to the pulp. In the field of dental health many theories prove that behavioral science is often ignored and that is a mistake. Not surprisingly, they are quite susceptible to experience in health status changes, including dental health. Therefore, dental health maintenance in children should involve the interaction of various parties, in which case the child itself, parents, and doctors. The prevalence of caries in children in developing countries is increasing rapidly. Nearly nine out of ten children suffered caries with seven of the 20 damaged teeth. This is also a proof of the lack of public behavior awareness to maintain oral health. As many as 90% of Indonesian children (ages 0-16 years) suffer from dental caries. Children who experience dental caries easily experience abnormal tooth growth, for example, protruded teeth. Etiology of Caries: the theory of caries etiology develops with the development of medical science. Parents role has a correlation with the dental caries experience status, periodontal status and students oral hygiene. First, socialization to the school concerned, principals and teachers about the intent and purpose of research conducted in the school. Figure 2: Scheme of dental caries Individual awareness, attitudes and behavior to wards dental health: Dental and oral health issues are closely related to social, psychological, cultural and economic factors. The character of the social structure and individual status in social status has a role to play as a symptom is shown and overcome. Since dental and oral problems are not a life-threatening problem, they are often ignored so it is important to provide a better understanding to the individual about how dental and oral health should be perceived. Every time we eat, food remnants and bacteria form an acidic substance that can dissolve minerals in tooth enamel and form a small, invisible hole. Table 2: Prevalence of Dental Caries by Gender Gender Male Female Total N 125999 87680 213679 D Total 604 472 1076 % 0. Table 3: Prevalence of Dental Caries by Occupation Type of Parents Code 1 2 3 4 5 Total N 219438 3875 9600 150 100 233163 D Total 752 100 192 20 12 1076 % 0. Table 4: Prevalence of Dental Caries Based on Parents Education Level Parents Education Level Bachelor Non-Bachelor Total n 287928 13312 301240 D Total 871 205 1076 % 0. The largest percentage of the 52 children with non- bachelor education level was 1. This indicates that the higher the educational level like bachelor the lower percentage of dental caries in the school. Table 5: Relationship between Prevalence of Dental Caries Based on Parents Education Level Correlations Prevalence of Dental caries Pearson Correlation Prevalence of Dental caries Level of Parent Education Sig. Ethical Clearance: Author was taken ethical clearance from Education Science Committee. The largest percentage of children`s dental caries cases based on age are at age 11 years of 2,71% or 37 children. The largest percentage of children`s dental caries based on gender is in girls of 0. The largest percentage of children`s dental caries based on parents occupation are in children whose parents work as private employees is 3. The Role of Food Patterns to Dental Caries on Children (The Role of Food Patterns to Dental Caries on Children). Tanti Ardiyanti Train the Child Maintain Cleanliness and Dental Health Since Early Age [Internet]. Scientific Scientific Dentistry (Scietific Journal in Dentistry) -September 2007 Wol. Analysis of Dental caries relationships and nutritional status of children aged 10-11 years Indian Journal of Public Health Research & Development, March 2020, Vol. Stroke is having significant impact on mortality, morbidity, also leads to physically and economically making the person as handicapped. Objectives: To estimate the prevalence, glycaemic control and risk factors of the diabetes mellitus among the stroke patients. Sample size of 134 among the stroke patients during the period of June 2018 to June 2019. Hypertension was significantly associated with diabetes among the stroke patients (P<0. Conclusions: Based on the study results,prevalence of diabetes among stroke patient was relatively little high, two thirds of diabetic patients were having poor glycaemic control. In addition to diabetes, we found high prevalence of hypertension, dyslipidaemia among the stroke patients. Abstract Introduction Stroke is an abrupt onset of neurological deficit that is attributed to a vascular cause. Chandra Sekhar Professor and Trainer at Family Medicine Academy, Buraidah, Qassim Province, Saudi Arabia. As a result of Diabetes incidence and prevalence, indirectly stroke patients are increasing. Need self care, adoption of preventive strategies and strict adherence of medication helpful for minimizing the disease associated complications. In view of huge morbidity and mortality patterns associated with Diabetes mellitus and economic burden on the families, there were many studies conducted to know the prevalence of Diabetes among community and hospitals in our kingdom and other countries. But, there is less available information about prevalence of diabetes mellitus among stroke patients. In view of the above situations, and due to the importance of the prevalence of diabetes mellitus among stroke patients and lack of much published information in our region. To estimate the prevalence of diabetes mellitus among stroke patients in King Fahad Specialist Hospital. To find the socio demographic characteristics, glycaemic control and other risk factors of Diabetes among the stroke patients. An interview based questionnaire was designed and information collected from the patients who were conscious. Those who were seriously ill, comatose patients, information taken from the close relatives of the patients. At 95% confidence level, 7% precision and an expected prevalence of 22% of diabetes among stroke patients. Inclusion Criteria: All stroke patients admitted in King Fahad Specialist hospital whose age above 20 years of age. Exclusion Criteria: Transient ischaemic patients, brain tumour patients Method of Data Collection: An interview questionnaire was prepared in consultation with the experts in the Family medicine department, Internal Medicine and neurologist working in the King Fahad specialist hospital and supervisor of the research project. All the study subjects were explained in detail about the purpose, importance and confidentiality about the disease.

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References

  • Sarkaria IS, Rizk NP, Grosser R, et al. Attaining proficiency in robotic-assisted minimally invasive esophagectomy while maximizing safety during procedure development. Innovations (Phila) 2016;11(4):268-273.
  • Salvarani C, Brown RD Jr, Calamia KT, et al. Primary central nervous system vasculitis: Analysis of 101 patients. Ann Neurol 2007;62:442-51.
  • Knudson MM, Ikossi DG, Khaw L, et al. Thromboembolism after trauma, an analysis of 1602 episodes from the American College of Surgeons National Trauma Data Bank. Ann Surg. 2004;240:490-498.
  • Ma H, Parsons MW, Christensen S, et al. A multicentre, randomized, double-blinded, placebo-controlled phase iii study to investigate extending the time for thrombolysis in emergency neurological deficits (extend). Int J Stroke 2012;7: 74-80.
  • Salonga D, Danenberg KD, Johnson M, et al. Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase. Clin Cancer Res 2000;6(4):1322-1327.
  • Hood V, Tannen R. Protection of acid-base balance by pH regulation of acid production. N Engl J Med. 1998;339:819-826.
  • Hughes RA, Bensa S, Willison HJ, et al. Randomized controlled trial of intravenous gammaglobulin vs oral prednisolone in chronic inflammatory demyelinating polyradiculoneuropathy. Ann Neurol. 2001;50:195-201.
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